Cushing’s syndrome is a condition in which the adrenal glands, which are present on top of each kidney, produce too much cortisol hormone. Normal levels of cortisol are produced when the body is in stress condition (such as any illness or operation), to regulate blood pressure, to fight infection (immune system) and to regulate weight, particularly fat distribution. When the level of corticosteroid increases because of too much intake of corticosteroids or tumors in pituitary gland, this can cause Cushing’s syndrome.
Pituitary gland is present in the brain which produces hormones (ACTH) that stimulates the adrenal glands to produce cortisol but because of pituitary tumor, it may produce too much ACTH, resulting in Cushing’s Syndrome.
Causes
- Excessive amount of cortisol hormone
- Use of corticosteroid
- Tumors like pituitary gland tumor, Ectopic tumor and Adrenal gland tumor
Symptoms
- Acne
- Weight gain
- Weakness in muscles
- Buffalo hump
- Chubby face sue to fatty deposits
- Skin becomes thin which can easily be bruised
- High level of sugar
- Depression and anxiety
- Hypertension
- Frequent urination
Treatment
- The use of corticosteroids is reduced
- Surgery
- Chemotherapy
- Radiation therapy
